Brain morphology and neurological soft signs in adolescents with first-episode psychosis

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Neurological soft signs in adolescents with first episode psychosis.

The purpose of this study is to determine the decrease of neurological soft signs (NSS) during adolescence and to compare this evolutionary process in two groups of adolescents with first episode psychosis: a) schizophrenia and b) non-schizophrenia patients. The structured neurological evaluation scale (NES) was administered to 24 adolescents with first episode psychosis. The number of NSS, the...

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Neurological soft signs and brain morphology in first-episode schizophrenia.

BACKGROUND Although minor motor and sensory deficits, or neurological soft signs (NSS), are a well-established finding in schizophrenia, the cerebral changes underlying these signs are only partly understood. We therefore investigated the cerebral correlates of NSS by using magnetic resonance imaging (MRI) in patients with schizophrenia and healthy controls. METHOD Forty-two patients, all rec...

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Neurological Soft Signs in First -Episode Schizophrenia

Neurological soft signs (NSS) refer to subtle neurological abnormalities comprising deficits in sensory integration, motor coordination, or sequencing of complex motor acts. It is generally accepted that NSS are more prevalent in schizophrenia patients, including first -episode cases, than in healthy subjects. Moreover, NSS have been consistently demonstrated in neuroleptic naïve firstepisode p...

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Neurological soft signs in Tunisian patients with first-episode psychosis and relation with cannabis use

BACKGROUND Neurological soft signs (NSS) are minor non-localizing neurological abnormalities that are conceptualized as neurodevelopmental markers that mediate the biological risk for psychosis. We aimed to explore the relationship between NSS and cannabis use, an environmental risk factor of psychosis. METHODS This was a cross-sectional study in consecutively admitted patients hospitalized f...

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Cerebellar substructures and neurological soft signs in first-episode schizophrenia.

A subtle impairment of motor coordination and sensory integration functions is frequently found in schizophrenia. Clinically these deficits present as neurological soft signs (NSS). Because of its crucial role in motor function, control of muscle tone and equilibrium, the cerebellum is likely to be involved in the appearance of NSS. Magnetic resonance imaging (MRI) was performed in 30 patients ...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2009

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.bp.108.052738